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Título:
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Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
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Autor/a:
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Gutiérrez, Juan Pablo; Nieto, Blanca; Piqueras, Pepa; Ibañez Escriche, Noelia; Salgado, Concepción
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Notas:
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The aim of this research was to explore the genetic parameters associated with environmental
variability for litter size (LS), litter weight (LW) and mean individual birth weight
(IW) in mice before canalisation. The analyses were conducted on an experimental mice population
designed to reduce environmental variability for LS. The analysed database included 1976
records for LWand IWand 4129 records for LS. The total number of individuals included in the
analysed pedigree was 3997. Heritabilities estimated for the traits under an initial exploratory
approach varied from 0.099 to 0.101 for LS, from 0.112 to 0.148 for LW and from 0.028 to
0.033 for IW. The means of the posterior distribution of the heritability under a Bayesian approach
were the following: 0.10 (LS), 0.13 (LW) and 0.03 (IW). In general, the heritabilities
estimated under the initial exploratory approach for the environmental variability of the analysed
traits were low. Genetic correlations estimated between the trait and its variability reached
values of –0.929 (LS), –0.815 (LW) and 0.969 (IW). The results presented here for the first
time in mice may suggest a genetic basis for variability of the evaluated traits, thus opening the
possibility to be implemented in selection schemes. |
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Materia(s):
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-Canalisation
-Variability
-Mice |
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Derechos:
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cc-by (c) Gutiérrez et al., 2006
http://creativecommons.org/licenses/by/3.0/es/
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Tipo de documento:
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article
publishedVersion |
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Editor:
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BioMed Central
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Compartir:
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