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Title:
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Carotenoid-enriched Transgenid Corn in Poultry Nutrition
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Author:
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Díaz Gómez, Joana; Moreno Martínez, José Antonio; Angulo Asensio, Eduardo; Sandmann, Gerhard; Portero Otín, Manuel; Capell Capell, Teresa; Zhu, Changfu; Christou, Paul; Nogareda, Carmina
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Notes:
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Vitamin A deficiency (VAD) is one of the most important micronutrient deficiencies globally. It is prevalent throughout the world, but it is particularly severe in Africa and South-East Asia. The main underlying cause of VAD is a chronic insufficient vitamin A intake in the diet, which can lead to disorders such as xerophthalmia, anaemia and weakened resistance to
infection. It has been estimated that VAD affects up to one third of the world’s pre-school-age children and up to 15% of pregnant women
1 .Vitamin fortification programs are unsustainable due to poor governance, inefficient food distribution networks, and the prevalence of subsistence agriculture
in rural populations 2 . Biofortification of staple
crops with organic nutrients is a cost-effective and sustainable approach as exemplified by Golden Rice 3 with high-levels of β-carotene, and Multivitamin Corn 4 accumulating high levels of β-carotene, zeaxanthin, lutein, lycopene, ascorbic acid, and folate. Vitamin A and carotenoid metabolism in chickens
is closely related to the equivalent processes in humans. Consequently chickens are also susceptible to vitamin A deficiency with similar symptoms.
We thank CESAC (Poultry Health Center of Catalonia and Aragon) for conducting the coccidia experiments; HIPRA Spain
for providing E. tenella sporulated oocysts; IRTA-Mas de Bover for diet formulation and manufacture; and X. Subirana, S. Isanta
andN. Duran for their involvement in the trials. This research was supported by grants BIO2011-22525 and PIM2010PKB-00746
CAROMAIZE, from Ministerio de Economia y Competitividad (MINECO), Spain; European Research Council IDEAS Advanced
Grant Program (BIOFORCE to P.C.); European Research Council IDEAS Proof of Concept Program (Multinutrient Maize to P.C.) and RecerCaixa PC084082. J D-G acknowledges the
Universitat de Lleida for a PhD fellowship. |
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Subject(s):
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-Blat de moro
-Plantes transgèniques
-Aviram
-Nutrició animal
-Corn
-Transgenic plants
-Poultry
-Animal nutrition |
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Rights:
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(c) Virginia Polytechnic Institute and State University, 2015
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Document type:
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Article
Article - Published version |
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Published by:
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Virginia Polytechnic Institute and State University
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