|
Title:
|
Comparison of cytospat and pipelle endometrial biopsy instruments
|
|
Author:
|
Antoni, Jordi; Folch, Eulalia; Costa, Jordi; Foradada, Carlos M.; Cayuela, Enric; Combalia, Neus; Rué i Monné, Montserrat
|
|
Notes:
|
OBJECTIVE:
To compare two endometrial biopsy techniques, based on the quality of material obtained, cost effectiveness, and pain during the procedure.
STUDY DESIGN:
A single blind, randomized prospective study.
RESULTS:
A total of 365 women with peri/postmenopausal bleeding were randomized into two groups: 174 biopsied cytospat (C) and 191 biopsied with pipelle (P). Both procedures were then followed by either dilatation and curettage (D&C) or hysterectomy. Pain was evaluated in 379 patients, with the result being better tolerance for P vs. C (3.55 vs. 4.06, P = 0.07). With C, the sensitivity in histological evaluation was 82% for benign endometrium, 60% for endometrial hyperplasia and 60% for corpus uterine neoplasia as compared to the D&C and hysterectomy material. With P the sensitivity was 84, 71 and 60%, respectively for the three diagnoses, as compared to the D&C and hysterectomy material. Insufficient tissue for pathologic evaluation was present in 24% of C, 25% of P and 9.8% of D&C samples.
CONCLUSIONS:
Cost effectiveness for pipelle is slightly higher than for Cytospat. |
|
Subject(s):
|
-Cytospat
-Endometrial hyperplasia
-Office endometrium biopsy
-Pipelle |
|
Rights:
|
(c) Elsevier Science Ireland Ltd., 1997
info:eu-repo/semantics/restrictedAccess |
|
Document type:
|
article
publishedVersion |
|
Published by:
|
Elsevier
|
|
Share:
|
|
