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Title:
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Iodine deficiency is higher in morbid obesity in comparison with late after bariatric surgery and non-obese women
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Author:
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Lecube Torelló, Albert; Zafon, Carles; Gromaz, Adoración; Fort, José Manuel; Caubet, Enric; Baena-Fustegueras, Juan A; Tortosa, Frederic
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Notes:
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Background Iodine deficiency and obesity are worldwideoccurring
health problems. Our purpose was to investigate
the relationship between morbid obesity and iodine status,
including subjects who lost weight after bariatric surgery.
Methods Ninety morbidly obese women, 90 women with at
least 18 months follow-up after bariatric surgery, and 45
healthy non-obese women were recruited. Urinary iodine
concentration (UIC) was measured in a spot urinary sample
and expressed as the iodine-to-creatinine ratio.
Results Obese women showed a significantly lower UIC in
comparison with non-obese women (96.6 (25.8–267.3) vs.
173.3 (47.0–493.6) μg/g; p<0.001), with a lesser proportion
of subjects with adequate iodine status (46.6 vs. 83.3 %,
p<0.001). The mean UIC significantly increased among
women who underwent bariatric surgery before the collection
of the urinary sample (96.6 (25.8–267.3) vs. 131.9 (62.9–
496.4) μg/g; p<0.001). No difference in UIC was detected
between laparoscopic Roux-en-Y gastric bypass and laparoscopic
sleeve gastrectomy. Univariate analysis showed that
UIC negatively correlated with body mass index (BMI)
(r=−0.278, p<0.001) and positively with age (r=0.206,
p=0.002). Finally, multiple linear regression analyses
showed that BMI was independently associated with
UIC (beta=−0.312, p<0.001; R2=0.166).
Conclusion Obesity is an independent risk factor to iodine
deficiency, almost in women.Whether more obese population
needs to be considered as a vulnerable group and whether
bariatric surgery can reverse iodine deficiency still remain to
be elucidated.
This study was supported by a grant from the Societat Catalana d’Endocrinologia i Nutrició (SCEN). |
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Subject(s):
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-Iodine
-Obesity
-Surgery |
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Rights:
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(C) Springer Science+Business Media New York, 2014
info:eu-repo/semantics/restrictedAccess |
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Document type:
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article
publishedVersion |
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Published by:
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Springer US
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