Reassessing the status of antiphospholipid syndrome in systemic lupus erythematosus.

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RECERCAT Home > Universitat de Barcelona > Medicina > Articles publicats en revistes (Medicina) > View document

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Title:	Reassessing the status of antiphospholipid syndrome in systemic lupus erythematosus.
Author:	Vianna, Joao L.; Haga, Hans J.; Tripathi, Poonam; Cervera i Segura, Ricard, 1960-; Khamashta, Munther A.; Hughes, Graham R. V. (Graham Robert Vivian)
Other authors:	Universitat de Barcelona
Abstract:	The antiphospholipid syndrome was initially described in 1986. To reassess the validity of antiphospholipid antibodies in systemic lupus erythematosus (SLE), 95 patients with SLE were studied. Their antiphospholipid antibody profile was analysed and correlated with clinical findings such as thrombosis, abortions, or thrombocytopenia. A low prevalence of these antibodies was found (13 patients; 14%) with a high specificity for thrombosis (92%) and abortions (92%). The importance of anticardiolipin antibodies as a risk factor for thrombosis or abortions, or both, in patients with SLE is reaffirmed by this work.
Subject(s):	-Lupus eritematós -Síndrome antifosfolipídica -Estudi de casos -Lupus erythematosus -Antiphospholipid syndrome -Case studies
Rights:	(c) BMJ Publishing Group Ltd, 1992
Document type:	Article Article - Published version
Published by:	BMJ Group
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