Title:
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Skin delivery of caffeine contained in biofunctional textiles
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Author:
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Valldeperas Morell, José; Rubio, Laia; Alonso, Cristina; Coderch, Luisa; Parra, José Luis; Martí, Meritxell; Cebrián, Juan; Navarro Viciana, Juan Antonio; Lis Arias, Manuel José
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Other authors:
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Universitat Politècnica de Catalunya. Departament d'Enginyeria Química; Universitat Politècnica de Catalunya. Institut d'Investigació Tèxtil i Cooperació Industrial de Terrassa; Universitat Politècnica de Catalunya. POLQUITEX - Materials Polimérics i Química Téxtil |
Abstract:
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Biofunctional textiles are materials with new properties and added value. In this work, emphasis was placed on the release capacity of the active principle (caffeine) from the formulation or from the biofunctional textile. In addition, a new in vitro methodology of percutaneous absorption was designed to demonstrate the delivery of encapsulated caffeine from the biofunctional textile to the different skin layers. In the first step, permeation studies through a nylon membrane were performed and the release capacity of caffeine present in the samples was quantified. In the second step, it was possible to detect the presence of caffeine in the different layers of the skin, while maintaining a close contact between the biofunctional textile and the skin by using pressure during the percutaneous absorption test. The new system is satisfactory for measuring the pass of the active principle from the biofunctional textile to the different skin layers. |
Abstract:
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Peer Reviewed |
Subject(s):
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-Àrees temàtiques de la UPC::Enginyeria tèxtil ::Teixits::Teixits mèdics -Textile fabrics -- Technological innovations -Biofunctional textile -Caffeine --Therapeutic use -Teixits i tèxtils -- Innovacions tecnològiques -Cafeïna |
Rights:
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Document type:
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Article - Published version Article |
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