In this article we develop tools to compute the Geometric Quantization of a symplectic manifold with respect to a regular Lagrangian foliation via sheaf cohomology. The starting point is the definition of representation spaces due to Kostant. We check that the associated sheaf cohomology apparatus satisfies Mayer-Vietoris and K\"unneth formulae. As a consequence, new proofs of classical results for fibrations are obtained. In the general case of Lagrangian foliations, we compute Geometric Quantization with respect to almost any generic regular Lagrangian foliation on a 2-torus.