Título:
|
An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines
|
Autor/a:
|
Amat Tusón, Mercedes; Pérez Bosch, Maria; Minaglia, Annamaria T.; Bosch Cartes, Joan
|
Otros autores:
|
Universitat de Barcelona |
Abstract:
|
A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position. |
Materia(s):
|
-Compostos organometàl·lics -Coure -Síntesi orgànica -Lactames -Organometallic compounds -Copper -Synthetic organic chemistry -Lactams |
Derechos:
|
(c) American Chemical Society , 2008
|
Tipo de documento:
|
Artículo Artículo - Versión aceptada |
Editor:
|
American Chemical Society
|
Compartir:
|
|