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Title:
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Computational modeling of electromechanical propagation in the helical ventricular anatomy of the heart
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Author:
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Marcé Nogué, Jordi; Fortuny Anguera, Gerard; Ballester Rodés, Manel; Carreras Costa, Francesc; Roure Fernández, Francisco
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Other authors:
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Universitat Politècnica de Catalunya. Departament de Resistència de Materials i Estructures a l'Enginyeria; Universitat Politècnica de Catalunya. LITEM - Laboratori per a la Innovació Tecnològica d'Estructures i Materials; Universitat Politècnica de Catalunya. REMM - Recerca en Estructures i Mecànica de Materials |
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Abstract:
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The classical interpretation of myocardial activation assumes that the myocardium is homogeneous and that the electrical propagation is radial. However, anatomical studies have described a layered anatomical structure resulting from a continuous anatomical helical disposition of the myocardial fibers. To further investigate the sequence of electromechanical propagation based on the helical architecture of the heart, a simplified computational model was designed. This model was then used to test four activation patterns, which were generated by propagating the action potential along the myocardial band from different activation sites. |
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Abstract:
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Peer Reviewed |
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Subject(s):
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-Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica
-Àrees temàtiques de la UPC::Ciències de la salut::Medicina
-Computational biology
-Myocardium
-Fibers
-Helical myocardial ventricular band
-Electro-mechanical sequence
-Activation
-Action potential
-Cardiac mechanics
-Biologia computacional |
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Rights:
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Document type:
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Article - Submitted version
Article |
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Published by:
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Elsevier
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