Título:
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Orthogonal protecting groups in the synthesis of tryptophanyl-hexahydropyrroloindoles
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Autor/a:
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Ruiz Sanchis, Pau; Savina, Svetlana A.; Acosta, Gerardo A.; Albericio Palomera, Fernando; Álvarez Domingo, Mercedes
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Otros autores:
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Universitat de Barcelona |
Abstract:
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The synthesis of various polycyclic systems containing a C3a-Ni bond between a hexahydropyrrolo[2,3-b]indole and an indole tryptophan is described here. A series of experiments were performed to determine the best combination of five orthogonal protecting groups and the best reaction conditions for formation of said bond, which is a common feature among many recently discovered marine natural products. |
Materia(s):
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-Productes naturals marins -Química heterocíclica -Aminoàcids -Síntesi de pèptids -Marine natural products -Heterocyclic chemistry -Amino acids -Peptide synthesis |
Derechos:
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(c) Wiley-VCH Verlag GmbH & Co. KGaA, 2012
info:eu-repo/semantics/embargoedAccess |
Tipo de documento:
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Artículo Artículo - Versión presentada |
Editor:
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Wiley-VCH
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Compartir:
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