Semiconductor technology evolution enables the design of sensor-based battery-powered ultra-low-cost chips (e.g., below 1 p) required for new market segments such as body, urban life and environment monitoring. Caches have been shown to be the highest energy and area consumer in those chips. This paper proposes a novel, hybrid-operation (high Vcc, ultra-low Vcc), single-Vcc domain cache architecture based on replacing energy-hungry bitcells (e.g., 10T) by more energy-efficient and smaller cells (e.g., 8T) enhanced with Error Detection and Correction (EDC) features for high reliability and performance predictability. Our architecture is proven to largely outperform existing solutions in terms of energy and area.