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Título:
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Textiles with gallic acid microspheres: in vitro release characteristics
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Autor/a:
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Marti Gelabert, Meritxell; Martínez Rodríguez, Vanessa; Carreras Parera, Núria; Alonso Merino, Cristina; Lis Arias, Manuel José; Parra Juez, José Luis; Coderch Negra, Luisa
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Otros autores:
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Universitat Politècnica de Catalunya. Departament d'Enginyeria Química; Universitat Politècnica de Catalunya. POLQUITEX - Materials Polimérics i Química Téxtil |
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Abstract:
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The aim of this study was to demonstrate the skin penetration of an antioxidant, gallic acid (GA), encapsulated in poly-epsilon-caprolactone (PCL) microspheres and applied onto textile fabrics, by a specific in vitro percutaneous absorption methodology. Two techniques (particle size distribution and FTIR) were used to characterise the microspheres obtained. The amount of GA-loaded microspheres present in the biofunctional textiles was established before their use as a textile drug delivery system. More absorption and desorption of microspheres with GA for the polyamide fabric were found in comparison with cotton fabric. The percutaneous absorption results indicated that the skin penetration of GA released from PCL-microspheres that were applied directly to the skin was higher than when GA was embedded within biofunctional textiles, in conclusion, an interesting reservoir effect may be promoted when biofunctional textiles were used. |
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Materia(s):
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-Àrees temàtiques de la UPC::Enginyeria tèxtil ::Teixits::Teixits mèdics
-Àrees temàtiques de la UPC::Enginyeria química::Indústries químiques::Química tèxtil
-Textile fibers - Technological innovations
-Textile industry--Technological innovations
-Skin absorption--Research
-Microspheres (Pharmacy)
-Biofunctional textiles
-microspheres
-percutaneous absorption
-reservoir effect
-BIOFUNCTIONAL TEXTILES
-ANTIOXIDANT
-LIPOSOMES
-DEVICES
-FABRICS
-SYSTEM
-COTTON
-SKIN
-Teixits i tèxtils intel·ligents
-Teixits i tèxtils -- Innovacions tecnològiques
-Absorció (Fisiologia) |
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Derechos:
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Tipo de documento:
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Artículo - Versión publicada
Artículo |
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