Energy efficiency is an essential topic nowadays. Several attempts have made to improve energy performance in buildings with particular attention to educational buildings for their high energy consumption. This thesis studies various buildings of the Technical University of Catalonia (UPC) with the aim of exploring the relationship between energy consumption and some parameters of the buildings such as floor area, occupancy, U-value, etc. The proposed methodology includes the definition of energy performance indicators based on data related to, energy consumption, weather data and buildings characteristics such as floor area, volume of the building and year of construction. Indicators are then applied to UPC buildings and finally obtained results are discussed. Results show that the occupancy and space use have a significant effect on energy consumption. Floor area and shape factor have also been found significantly influence the energy consumption. Moreover, the study compares the annual energy consumption in the north campus between 2011, 2012 and 2013, demonstrating that despite implementation of Energy Optimization Projects (POE), the energy consumption has increased in the north campus buildings.