Title:
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Adherence to Childhood Tuberculosis Treatment in Mozambique
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Author:
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López-Varela, Elisa; Sequera, Víctor Guillermo; García-Basteiro, Alberto L.; Augusto, Orvalho; Munguambe, Khátia; Sacarlal, Jahit; Alonso, Pedro
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Abstract:
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BACKGROUND: There is limited literature regarding adherence
rates for the treatment of tuberculosis (TB) in children. We
aimed to describe TB treatment outcomes and adherence as well as
to evaluate associated factors to poor adherence in Mozambican
children. METHODS: This is a sub-study of a community TB
incidence study among children <3 years of age. Incomplete
adherence included the sum of lost-to-follow-up cases plus those
with a delay of > 3 weeks to treatment completion. RESULTS:
Fifty TB treatments were assessed. Forty-four (88.0%) patients
completed treatment, two (4.0%) died during treatment and four
(8.0%) were lost to follow-up. Incomplete adherence was observed
in 31.3% (15 of 48) of cases and was associated with
malnutrition or history of a migrant mother. CONCLUSION:
Although treatment outcome is overall good, there is still a
significant proportion of incomplete adherence. Further larger
paediatric TB cohorts and qualitative approaches are needed to
assess and confirm potential factors for non-adherence. |
Subject(s):
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-Infància -Tuberculosi -Moçambic -Childhood -Tuberculosis -Mozambique |
Rights:
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(c) López-Varela et al., 2016
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Document type:
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Article Article - Accepted version |
Published by:
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Oxford University Press
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