Characterization data of gilthead sea bream (Sparus aurata) IGF-I receptors (IGF-IRa/Rb)

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Title:	Characterization data of gilthead sea bream (Sparus aurata) IGF-I receptors (IGF-IRa/Rb)
Author:	Vélez, Emilio J.; Azizi, Sheida; Salmerón, Cristina; Chan, Shu Jin; Nematollahi, Mohammad Ali; Amiri, Bagher Mojazi; Navarro Álvarez, Isabel; Capilla Campos, Encarnación; Gutiérrez Fruitós, Joaquín
Other authors:	Universitat de Barcelona
Abstract:	In this data article we describe the coding sequence of two IGF-IR paralogues (IGF-IRa and IGF-IRb) obtained from gilthead sea bream embryos. The putative protein architecture (domains and other important motifs) was determined and, amino acid sequences alignment and phylogenetic analysis of both receptors together with IGF-IR orthologues from different vertebrates was performed. Additionally, a semi-quantitative conventional PCR was done to analyze the mRNA expression of both receptors in different tissues of gilthead sea bream. These data will assist in further physiological studies in this species. In this sense, the expression of both receptors during ontogeny in muscle as well as the differential effects of IGF-I and IGF-II on their regulation during in vitro myogenesis has been recently studied
Subject(s):	-Orada -Expressió gènica -Receptors d'insulina -Miogènesi -Sparus aurata -Gene expression -Insulin receptors -Myogenesis
Rights:	cc-by (c) Vélez et al., 2016 http://creativecommons.org/licenses/by/3.0/es
Document type:	Article Article - Published version
Published by:	Elsevier
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