Long Short--Term Memory (LSTM) is a recurrent neural network that uses structures called memory blocks to allow the net remember significant events distant in the past input sequence in order to solve long time lag tasks, where other RNN approaches fail. Throughout this work we have performed experiments using LSTM networks extended with growing abilities, which we call GLSTM. Four methods of training growing LSTM has been compared. These methods include cascade and fully connected hidden layers as well as two different levels of freezing previous weights in the cascade case. GLSTM has been applied to a forecasting problem in a biomedical domain, where the input/output behavior of five controllers of the Central Nervous System control has to be modelled. We have compared growing LSTM results against other neural networks approaches, and our work applying conventional LSTM to the task at hand.