A computer cluster is a group of interconnected computers. They work as a single supercomputer that can run simulations and operations that require big computational calculations. A computer cluster has several applications from climatological predictions and astrological applications to molecular simulations. On the other hand, the Raspberry Pi 2 is a computer with the size of a credit card but with a high performance. At the Escola Tècnica i Superior d’Enginyeria Industrial de Barcelona (Spain) was born the idea of building a small computer cluster for small research centres and universities by using a hundred Raspberry Pi 2 boards: The E-Nanocluster. The E-Nanocluster requires a series of projects that delve into different branches of the engineering science. This particular project is the first one and it focus on the heat extraction and the structure design of the cluster. The structure of this document follows all the steps that bring the cluster from a simple idea to a real solution. First there is a presentation of the main characteristics of the computer clusters and the Raspberry Pi 2 boards and then is analysed the state of the art of the actual heat extraction systems in computers. Once the best system is chosen, it is provided a basic design for the cluster. From that design is developed an adaptable thermal and fluidic model made with Microsoft Office Spreadsheet. This model calculates in just a few seconds which is the fan power required for the correct heat extraction. All the parameters such as the air temperature, heat sink characteristics or the power generated can be modified. With this model it is done a sensibility analysis for optimizing the solution by minimizing the cost and the space of the machine. After that, it has been done a Computational Fluid Dynamic (CFD) simulation to verify the model. The CFD program used has been SolidWorks Flow Simulation. Finally, there is an analysis of the environmental impact, the budget of the project and a plan for the next projects that should be done for bringing the E-Nanocluster to life.