Title:
|
Estimation of wall shear stress using 4D flow cardiovascular MRI and computational fluid dynamics
|
Author:
|
Soudah Prieto, Eduardo; Casacuberta Puig, Jordi; Gámez Montero, Pedro Javier; Raush Alviach, Gustavo Adolfo; Castilla López, Roberto
|
Other authors:
|
Universitat Politècnica de Catalunya. Departament de Resistència de Materials i Estructures a l'Enginyeria; Universitat Politècnica de Catalunya. Departament de Mecànica de Fluids; Universitat Politècnica de Catalunya. GMNE - Grup de Mètodes Numèrics en Enginyeria; Universitat Politècnica de Catalunya. LABSON - Laboratori de Sistemes Oleohidràulics i Pneumàtics |
Abstract:
|
Electronic version of an article published as Journal of mechanics in medicine and biology, 0, 1750046 (2016), 16 pages. DOI:10.1142/S0219519417500464
© World Scientific Publishing Company |
Abstract:
|
In the last few years, wall shear stress (WSS) has arisen as a new diagnostic indicator in patients with arterial disease. There is a substantial evidence that the WSS plays a significant role, together with hemodynamic indicators, in initiation and progression of the vascular diseases. Estimation of WSS values, therefore, may be of clinical significance and the methods employed for its measurement are crucial for clinical community. Recently, four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) has been widely used in a number of applications for visualization and quantification of blood flow, and although the sensitivity to blood flow measurement has increased, it is not yet able to provide an accurate three-dimensional (3D) WSS distribution. The aim of this work is to evaluate the aortic blood flow features and the associated WSS by the combination of 4D flow cardiovascular magnetic resonance (4D CMR) and computational fluid dynamics technique. In particular, in this work, we used the 4D CMR to obtain the spatial domain and the boundary conditions needed to estimate the WSS within the entire thoracic aorta using computational fluid dynamics. Similar WSS distributions were found for cases simulated. A sensitivity analysis was done to check the accuracy of the method. 4D CMR begins to be a reliable tool to estimate the WSS within the entire thoracic aorta using computational fluid dynamics. The combination of both techniques may provide the ideal tool to help tackle these and other problems related to wall shear estimation. |
Abstract:
|
Peer Reviewed |
Subject(s):
|
-Àrees temàtiques de la UPC::Enginyeria mecànica::Mecànica de fluids -Àrees temàtiques de la UPC::Enginyeria biomèdica::Biomecànica -Fluid dynamics -Cardiovascular system -Phase-contrast MRI -Velocity mapping -Blood flow patterns -Wall shear stress -Computational fluid dynamics -Dinàmica de fluids -Sistema cardiovascular |
Rights:
|
|
Document type:
|
Article - Submitted version Article |
Share:
|
|