Two deformation events have been documented in the NW Persian Gulf during the Late Cretaceous and the Late Cenozoic. The most distinctive feature in this part of the Persian Gulf is the reactivation of the Late Cretaceous NNE-SSW Arabian trending folds by NE-SW shortening during the Late Cenozoic Zagros Orogeny. In general, if a set of folds with horizontal axes is shortened roughly parallel to its fold axis, a dome-basin fold interference pattern is produced. In the NW Persian Gulf, reactivation of some old folds occurred instead of a fold interference pattern. Reactivation may be influenced by the following factors: 1) the presence of incompetent layers (i.e. evaporites), 2) a variable overburden, 3) basement faults, and 4) obliquity between the younger deformation shortening axis and fold axis. It is this later factor that we investigated by means of analogue modelling. The experimental apparatus is similar to that commonly used for experiments with brittle-ductile systems at the Laboratory of Experimental Tectonics of Géosciences Rennes. The model consisted of an alternation of ductile and brittle horizontal layers with a stratigraphy similar to the one found in the NW Persian Gulf. The model was deformed by two deformation events with an angle α between the two directions of shortening. After deformation, the resulting structure resembled a fold facing the static wall with internal thrust faults and detachment faults arranged into a geometry similar to a fish-tail. In the second shortening event, the fold was reactivated without formation of an interference pattern. Moreover, the displacement on both the reactivated and newly formed faults varied between almost pure thrust faults for low α and oblique thrust faults with a strike-slip component for high α. The models suggest that the presence of incompetent layers plays an important role in fold reactivation and confirm that basement faults are not necessary.