The current global economic crisis has led us to ask how to generate competitive advantages with an impact on organizational effectiveness without jeopardizing the employees' quality of life. The importance of the development of health and safety policies (Montero, Araque, & Rey, 2009), among them, those relating to family-friendly policies promoting work-life balance (WLB) of employees (Leon & Chinchilla, 2010; Urcelay, 2005) has been pointed out by various authors in our country. This article reviews the main Spanish and Latin American contributions on work-life balance (WLB) published in the last eight years, and presents the research work of ASH-PsicoSAO Group (University of Barcelona) related to this topic. The objective of our work is to contribute to both, the scientific and the occupations fields, with particular attention to the role of supervisor.