Title:
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psygenet2r: a R/Bioconductor package for the analysis of psychiatric disease genes
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Author:
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Gutiérrez Sacristán, Alba; Hernández Ferrer, Carles; González, Juan Ramón; Furlong, Laura I.
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Abstract:
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Motivation: Psychiatric disorders have a great impact on
morbidity and mortality. Genotype-phenotype resources for
psychiatric diseases are key to enable the translation of
research findings to a better care of patients. PsyGeNET is a
knowledge resource on psychiatric diseases and their genes,
developed by text mining and curated by domain experts. Results:
We present psygenet2r, an R package that contains a variety of
functions for leveraging PsyGeNET database and facilitating its
analysis and interpretation. The package offers different types
of queries to the database along with variety of analysis and
visualization tools, including the study of the anatomical
structures in which the genes are expressed and gaining insight
of gene's molecular function. Psygenet2r is especially suited
for network medicine analysis of psychiatric disorders.
Availability: The package is implemented in R and is available
under MIT license from Bioconductor (
http://bioconductor.org/packages/release/bioc/html/psygenet2r.html ). Supplementary information: Supplementary data are available at Bioinformatics online. |
Subject(s):
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-Psiquiatria -Genètica mèdica -Psychiatry -Medical genetics |
Rights:
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cc by (c) Gutierrez et al., 2017
http://creativecommons.org/licenses/by/4.0/ |
Document type:
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Article Article - Published version |
Published by:
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Oxford University Press
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