Título:
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Diagnosis of Trypanosoma cruzi Infection Status using Saliva of
Infected Subjects
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Autor/a:
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Cortés Serra, Núria; Pinazo, María Jesús; Torre, Leonardo de la; Galizzi, Melina; Gascón i Brustenga, Joaquim; Bustamante, Juan Manuel
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Abstract:
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Chagas disease has the highest prevalence of any parasitic
disease in the Americas, affecting 6-7 million people.
Conventional diagnosis requires a well-equipped laboratory with
experienced personnel. The development of new diagnostic tools
that are easy to use and adapted to the reality of affected
populations and health systems is still a significant challenge.
The main objective of this study was to measure Trypanosoma
cruzi infection status using saliva samples of infected
subjects. Blood and saliva samples from 20 T. cruzi-seropositive
individuals and 10 controls were tested for T. cruzi infection
using two different commercial serological tests. We have shown
that detection of T. cruzi infection is possible using saliva
samples, supporting the potential use of saliva to diagnose
Chagas disease in humans. This method could provide a simple,
low-cost but effective tool for the diagnosis of T. cruzi
infection. Its noninvasive nature makes it particularly well
suited for endemic areas. |
Materia(s):
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-Malaltia de Chagas -Saliva -Chagas' disease -Saliva |
Derechos:
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(c) The American Society of Tropical Medicine and Hygiene, 2018
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Tipo de documento:
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Artículo Artículo - Versión aceptada |
Editor:
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American Society of Tropical Medicine and Hygiene
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