Title:
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Hydroxyl-functionalized amphiphilic triblock copolyesters made of tartaric and lactic acids: Synthesis and nanoparticle formation
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Author:
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Zakharova, Elena; Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon; León Cavanillas, Salvador; Muñoz Guerra, Sebastián
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Other authors:
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Universitat Politècnica de Catalunya. Departament d'Enginyeria Química; Universitat Politècnica de Catalunya. POL - Polímers Industrials Avançats i Biopolímers Tecnològics |
Abstract:
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Bio-based triblock copolyesters were synthesized by ring-opening polymerization of l-lactide in solution using a hydroxyl-ended polytartrate as di-functional macroinitiator. This telechelic polyester with a Mn about 3000¿g·mol-1 was obtained by non-stoichiometric melt polycondensation of dimethyl 2,3-di-O-isopropylidene-l-tartrate and 1,4-butanediol. Two symmetrical triblock copolyesters with Mn in the 5000–7000¿g·mol-1 range and differing in the length of the polylactide blocks were prepared. The protecting isopropylidene group was removed in trifluoracetic acid to generate amphiphilic triblock copolyesters bearing free hydroxyl groups in the central block. All copolyesters started to decompose approximately at 260–280¿°C, were semicrystalline, and readily degraded by hydrolysis of the main chain under both acid and basic conditions. The acetalized copolyesters had a single Tg, whereas free-hydroxyl bearing copolyesters showed two Tg indicative of blocks phase separation. All copolyesters were able to form nanoparticles with average diameters within the ~200–450¿nm range. The influence of the block lengths and protection/deprotection of the hydroxyl groups on size and ¿-potential of the nanoparticles was evaluated. |
Abstract:
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Peer Reviewed |
Subject(s):
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-Àrees temàtiques de la UPC::Enginyeria química -Lactic acid -Nanoparticles -Copolymers -Amphiphilic -block copolyesters -tartaric acid -lactic acid -nanoparticles -Polièsters -Nanopartícules -Copolímers |
Rights:
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Attribution-NonCommercial-NoDerivs 3.0 Spain
http://creativecommons.org/licenses/by-nc-nd/3.0/es/ |
Document type:
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Article - Submitted version Article |
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