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Title:	Leisure-time vigorous physical activity is associated with better lung function: The prospective ECRHS study
Author:	Fuertes, Elaine; Carsin, Anne-Elie; Antó i Boqué, Josep Maria; García Aymerich, Judith
Abstract:	OBJECTIVE: We assessed associations between physical activity and lung function, and its decline, in the prospective population-based European Community Respiratory Health Survey cohort. METHODS: FEV1 and FVC were measured in 3912 participants at 27-57 years and 39-67 years (mean time between examinations=11.1 years). Physical activity frequency and duration were assessed using questionnaires and used to identify active individuals (physical activity ≥2 times and ≥1 hour per week) at each examination. Adjusted mixed linear regression models assessed associations of regular physical activity with FEV1 and FVC. RESULTS: Physical activity frequency and duration increased over the study period. In adjusted models, active individuals at the first examination had higher FEV1 (43.6 mL (95% CI 12.0 to 75.1)) and FVC (53.9 mL (95% CI 17.8 to 89.9)) at both examinations than their non-active counterparts. These associations appeared restricted to current smokers. In the whole population, FEV1 and FVC were higher among those who changed from inactive to active during the follow-up (38.0 mL (95% CI 15.8 to 60.3) and 54.2 mL (95% CI 25.1 to 83.3), respectively) and who were consistently active, compared with those consistently non-active. No associations were found for lung function decline. CONCLUSION: Leisure-time vigorous physical activity was associated with higher FEV1 and FVC over a 10-year period among current smokers, but not with FEV1 and FVC decline.
Abstract:	This project has received funding from the european Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-curie individual Fellowship scheme (elaine Fuertes, H2020- MSca-iF-2015; proposal number 704268). the present analyses are part of the ageing lungs in european cohorts (alec) Study (www.alecstudy.org), which has also received funding from the european Union's Horizon 2020 research and innovation programme under grant agreement no 633212. the local investigators and funding agencies for the european community respiratory Health Survey (ecrHS ii and ecrHS iii) are reported in the online supplementary file.
Subject(s):	-Respiratory physiology -Physical activity -Lung function
Rights:	© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/
Document type:	Article Article - Published version
Published by:	BMJ Publishing Group
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