Títol:
|
A method for small-animal PET/CT alignment calibration. Physics in medicine & biology
|
Autor/a:
|
Pascau, J.; Vaquero, Juan J.; Chamorro Servent, Judit; Rodríguez-Ruano, A.; Desco, Manuel
|
Abstract:
|
Small-animal positron-emission tomography/computed tomography (PET/
CT) scanners provide anatomical and molecular imaging, which enables the
joint visualization and analysis of both types of data. A proper alignment
calibration procedure is essential for small-animal imaging since resolution
is much higher than that in human devices. This work presents an alignment
phantom and two different calibration methods that provide a reliable and
repeatable measurement of the spatial geometrical alignment between the PET
and the CT subsystems of a hybrid scanner. The phantom can be built using
laboratory materials, and it is meant to estimate the rigid spatial transformation
that aligns both modalities. It consists of three glass capillaries filled with a
positron-emitter solution and positioned in a non-coplanar triangular geometry
inside the system field of view. The calibration methods proposed are both
based on automatic line detection, but with different approaches to calculate
the transformation of the lines between both modalities. Our results show an
average accuracy of the alignment estimation of 0.39 mm over the whole field
of view. |
Abstract:
|
This study was funded by CDTI under the CENIT Program (AMIT Project), projects
ARTEMIS S2009/DPI-1802 (CAM) and TEC2010-21619-C04-01, and supported by the
Spanish Ministry of Economy and Competitiveness. |
Drets:
|
© Institute of Physics (IOP)
http://dx.doi.org/10.1088/0031-9155/57/12/N199 |
Tipus de document:
|
Article Article - Versió acceptada |
Publicat per:
|
Institute of Physics (IOP)
|
Compartir:
|
|