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Título:
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Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study.
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Autor/a:
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Podlipnik, Sebastian; Carrera, Cristina; Boada, Aram; Richarz, Nina; Marcoval, Joaquim; Ferreres, Josep Ramón; Bodet, Domingo; Martí Laborda, Rosa Ma.; Segura, Sonia; Sabat, Mireia; Dalmau, Joan; Quintana, Mònica; Azon, Antoni; Curcó, Neus; Formigon, Manel; Olivella-Garcés, María Rosa; Zaballos, Pedro; Sola, Joaquim; Galvany, Loida; Baliu-Piqué, Carola; Alegre, Marta; Pasquali, Paola; Malvehy, Josep; Puig, Susana
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Otros autores:
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Network of Melanoma Centres of Catalonia |
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Notas:
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The incidence of melanoma has been increasing worldwide during recent decades. The objective of the study was to analyse the trends in incidence for in situ and invasive melanoma in the Spanish region of Catalonia during the period of 2008-2017. We designed a cross-sectional study with an age-period-cohort analysis of melanoma patient data from the Network of Melanoma Centres in Catalonia. Our database covered a population of over seven million and included a total of 8626 patients with incident melanoma. The main outcome measures were crude and age-standardised incidence rates to the European 2013 standard population. Joinpoint regression models were used to evaluate the population trends. We observed an increase in the age-standardised incidence rate (per 100,000 population) of all melanoma subtypes from 11.56 in 2008 to 13.78 in 2017 with an average annual percent change (AAPC) of 3.5%. This incidence increase was seen exclusively in the older population. Moreover, the stratified analysis showed a statistically significant increase in the age-standardised incidence rate for invasive (AAPC 2.1%) and in situ melanoma (AAPC 6.5%). In conclusion, the incidence of melanoma has continued to increase in the elderly population over recent decades, with a rapidly increasing trend of in situ melanomas and the lentigo maligna subtype.
The study in the Melanoma Unit, Hospital Clínic, Barcelona was supported in part by grants from Fondo de Investigaciones Sanitarias P.I. 12/00840, PI 15/00956, and PI 15/00716 Spain; by the CIBER de Enfermedades Raras of the Instituto de Salud Carlos III, Spain, co-funded by “Fondo Europeo de Desarrollo Regional (FEDER).
Unión Europea. Una manera de hacer Europa”; by the AGAUR 2014_SGR_603 and 017_SGR_1134 of the Catalan Government, Spain; by a grant from “Fundació La Marató de TV3, 201331-30”, Catalonia, Spain; by the European Commission under the 6th Framework Programme, Contract no
: LSHC-CT-2006-018702 (GenoMEL); by CERCA
Programme/Generalitat de Catalunya; by a Research Grant from “Fundación Científica de la Asociación Española Contra el Cáncer” GCB15152978SOEN, Spain; by a grant from the European Academy of Dermatology and
Venereology (EADV) (PPRC-2017/19). Part of the work was developed at the building Centro Esther Koplowitz. Melanoma research at the Department of Dermatology of Hospital Universitari Arnau de Vilanova de Lleida is supported by grants from ISCIII (PI15/00711 to RMM, cofinanced by FEDER “Una manera de hacer Europa” and CIBERONC- CB16/12/00231) and from Fundació la Marató de TV3 (FMTV 201331-31 to RMM). |
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Materia(s):
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-Melanoma
-Incidence
-Population-based study
-Epidemiology
-Spain
-Skin cancer |
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Derechos:
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cc-by (c) Podlipnik, Sebastian et al., 2020
http://creativecommons.org/licenses/by/4.0/
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Tipo de documento:
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Artículo
Artículo - Versión publicada |
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Editor:
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MDPI
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Compartir:
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