Para acceder a los documentos con el texto completo, por favor, siga el siguiente enlace: http://hdl.handle.net/2445/120039

Título:	In vitro comparative skin irritation induced by micro and nano zinc oxide
Autor/a:	Vinardell Martínez-Hidalgo, Ma. Pilar; Llanas Marco, Hector; Marics, Laura; Mitjans Arnal, Montserrat
Otros autores:	Universitat de Barcelona
Abstract:	This study was designed to determine whether nano-sized ZnO has the potential to cause acute cutaneous irritation using cultured HaCaT keratinocytes and a human skin equivalent as in vitro models, compared to non-nanomaterials. Commercial nano ZnO with different sizes (50 nm and 100 nm) was characterized by dynamic light scattering (DLS) and microscopy (SEM) in different media. Nano ZnO reduced the cell viability of HaCaT in a dose-dependent and time-dependent manner, in a similar way to macro ZnO. However, the 3D-epidermis model revealed no irritation at 1 mg/mL after 24 h of exposure. In conclusion, nano-sized ZnO does not irritate skin, in a similar manner to non-nano ZnO.
Materia(s):	-Òxid de zinc -Malalties de la pell -Zinc oxide -Skin diseases
Derechos:	cc-by (c) Vinardell Martínez-Hidalgo, Ma. Pilar et al., 2017 http://creativecommons.org/licenses/by/3.0/es
Tipo de documento:	Artículo Artículo - Versión publicada
Editor:	MDPI
Compartir:

Mostrar el registro completo del ítem