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Title:	Low-Dose PET/CT and Full-Dose Contrast-Enhanced CT at the Initial Staging of Localized Diffuse Large B-Cell Lymphomas
Author:	Sabaté Llobera, Aida; Cortés Romera, Montserrat; Mercadal, Santiago; Hernández Gañán, Javier; Pomares, Helena; González Barca, Eva; Gámez, Cristina
Abstract:	Computed tomography (CT) has been used as the reference imaging technique for the initial staging of diffuse large B-cell lymphoma until recent days, when the introduction of positron emission tomography (PET)/CT imaging as a hybrid technique has become of routine use. However, the performance of both examinations is still common. The aim of this work was to compare the findings between low-dose 2-deoxy-2-(F-18) fluoro-D-glucose (F-18-FDG) PET/CT and full-dose contrast-enhanced CT (ceCT) in 28 patients with localized diffuse large B-cell lymphoma according to PET/CT findings, in order to avoid the performance of ceCT. For each technique, a comparison in the number of nodal and extranodal involved regions was performed. PET/CT showed more lesions than ceCT in both nodal (41 vs. 36) and extranodal localizations (16 vs. 15). Disease staging according to both techniques was concordant in 22 patients (79%) and discordant in 6 patients (21%), changing treatment management in 3 patients (11%). PET/CT determined a better staging and therapeutic approach, making the performance of an additional ceCT unnecessary.
Subject(s):	-Limfomes -Tomografia -Lymphomas -Tomography
Rights:	cc-by-nc (c) Sabaté Llobera et al., 2016 http://creativecommons.org/licenses/by-nc/3.0/es
Document type:	Article Article - Published version
Published by:	Libertas Academica Limited
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