Utilizad este identificador para citar o enlazar este documento: http://hdl.handle.net/2072/355070

Título:	Morin flavonoid adsorbed on mesoporous silica, a novel antioxidant nanomaterial
Autor/a:	Arriagada, Francisco; Correa, Olosmira; Günther, Germán; Nonell, Santi; Mura, Francisco; Olea-Azar, Claudio; Morales, Javier
Otros autores:	Universitat Ramon Llull. IQS
Abstract:	Morin (2´,3, 4´,5,7-pentahydroxyflavone) is a flavonoid with several beneficial health effects. However, its poor water solubility and it sensitivity to several environmental factors avoid its use in applications like pharmaceutical and cosmetic. In this work, we synthetized morin-modified mesoporous silica nanoparticles (AMSNPs-MOR) as useful material to be used as potential nanoantioxidant. To achieve this, we characterized its adsorption kinetics, isotherm and the antioxidant capacity as hydroxyl radical (HO•) scavenger and singlet oxygen (¹O2) quencher. The experimental data could be well fitted with Langmuir, Freundlich and Temkin isotherm models, besides the pseudo-second order kinetics model. The total quenching rate constant obtained for singlet oxygen deactivation by AMSNPs-MOR was one order of magnitude lower than the morin rate constant reported previously in neat solvents and lipid membranes. The AMSNPs-MOR have good antioxidant properties by itself and exhibit a synergic effect with morin on the antioxidant property against hydroxyl radical. This effect, in the range of concentrations studied, was increased when the amount of morin adsorbed increased.
Fecha de creación:	03-11-2016
Materias (CDU):	546 - Química inorgànica
Materia(s):	Flavonoides Cosmètica Compostos químics
Derechos:	L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/ © L'autor/a
Páginas:	22 p.
Tipo de documento:	Artículo Artículo - Versión publicada
DOI:	https://doi.org/10.1371/journal.pone.0164507
Editor:	PLOS (Public Library of Science)
Publish at:	Plos One, 2016, vol.11
Compartir:

Documentos con el texto completo de este documento

Mostrar el registro completo del ítem