Case report: A 31 year old Spanish woman attended Hospital Clinic in Barcelona in August 2018, after working in La Paz (Bolivia) for six months. She remembered an insect bite on her right thigh, during a trip to Beni (Brazilian border) with progression to a papule with a central crater within one month. Treatment with oral moxicillin/clavulanic acid yielded no improvement. Thereupon, a diagnostic puncture of the ulcer was performed, with a positive result of polymerase chain eaction (PCR) for Leishmania spp. without bacterial isolates in the culture. She then decided to return to Spain for management.