Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering

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dc.contributor.author	Rao, Satish
dc.contributor.author	Raj, Saurabh
dc.contributor.author	Balint, Stefan
dc.contributor.author	Bardina Fons, Carlota
dc.contributor.author	Campoy Sánchez, Susana
dc.contributor.author	Llagostera Casas, Montserrat
dc.contributor.author	Petrov, Dmitri
dc.contributor.author	American Physical Society
dc.date	2010
dc.identifier	https://ddd.uab.cat/record/115983
dc.identifier	urn:10.1063/1.3431628
dc.identifier	urn:oai:ddd.uab.cat:115983
dc.identifier	urn:recercauab:ARE-56783
dc.identifier	urn:articleid:10773118v96n21p213701/1
dc.identifier	urn:scopus_id:77956260170
dc.identifier	urn:wos_id:000278183200093
dc.identifier	urn:oai:egreta.uab.cat:publications/4f7c64d6-9df3-4a52-8766-903c4d420c26
dc.format	application/pdf
dc.language	eng
dc.publisher
dc.relation	Applied physics letters ; Vol. 96, Issue 21 (May 2010), p. 213701/1-213701/3
dc.rights	open access
dc.rights	Tots els drets reservats.
dc.rights	https://rightsstatements.org/vocab/InC/1.0/
dc.subject	DNA
dc.subject	Silver
dc.subject	Colloidal systems
dc.subject	Raman spectra
dc.subject	Surface enhanced
dc.subject	Raman scattering
dc.subject	Metal surfaces
dc.subject	Elasticity
dc.subject	Metal optics
dc.subject	Scattering measurements
dc.title	Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering
dc.type	Article
dc.description.abstract	Raman spectra from single DNA molecules in their natural aqueous environment are presented. A DNA molecule that is anchored between two optically trapped dielectric beads is suspended in a solution with nanosized silvercolloid particles. The nonspecific binding of the metal to the DNA enhances the Raman scattering that is excited by a near-infrared beam. A Raman spectrum is first recorded followed by a force-extension curve that verifies the presence of a single DNA molecule.

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