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| Título: | The neural correlates of delay discounting in obesity and binge eating disorder |
|---|---|
| Autor/a: | Miranda-Olivos, Romina; Steward, Trevor; Martínez-Zalacaín, Ignacio; Mestre-Bach, Gemma; Juaneda-Seguí, Asier; Jiménez-Murcia, Susana; Fernández-Formoso, José A.; Vilarrasa, Nuria; Veciana de las Heras, Misericordia; Custal, Nuria; Virgili, Nuria; Lopez-Urdiales, Rafael; Menchón, José M.; Granero, Roser; Soriano-Mas, Carles; Fernández-Aranda, Fernando |
| Abstract: | Increased delay discounting is associated with obesity and binge eating disorder (BED). Although BED and obesity frequently co-occur, the neural mechanisms underlying delay discounting in these conditions remain poorly understood. Thirtyfive women with obesity, including 10 participants with obesity and BED and 31 controls completed a monetary delay discounting task during functional magnetic resonance imaging. We identified that increased discounting rates were associated with decreased activity in the left anterior insula in participants with obesity compared to controls when choosing immediate rewards over delayed rewards (P < 0.05). An exploratory analysis comparing the BED subsample to the other groups did not detect significant differences. Our findings suggest decreased activity in the anterior insula may underlie heightened delay discounting in individuals with obesity, contributing the probability of choosing immediate rewards over delayed rewards based on emotional states. Future studies including larger, more diverse samples are required to confirm these effects. |
| Materia(s): | -Delay discounting -Obesity -Binge eating disorder -Eating disorders -Fmri |
| Derechos: | open access
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. https://creativecommons.org/licenses/by-nc/4.0/ |
| Tipo de documento: | Article |
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| Uri: | https://ddd.uab.cat/record/265999 |
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