To access the full text documents, please follow this link: http://hdl.handle.net/2445/130565
| dc.contributor.author | Tejera Vaquerizo, Antonio |
|---|---|
| dc.contributor.author | Nagore, Eduardo |
| dc.contributor.author | Puig i Sardà, Susana |
| dc.contributor.author | Robert, Caroline |
| dc.contributor.author | Saiag, Philippe |
| dc.contributor.author | Martín-Cuevas, Paula |
| dc.contributor.author | Gallego, Elena |
| dc.contributor.author | Herrera Acosta, Enrique |
| dc.contributor.author | Aguilera, José |
| dc.contributor.author | Malvehy, J. (Josep) |
| dc.contributor.author | Carrera Álvarez, Cristina |
| dc.contributor.author | Cavalcanti, Andrea |
| dc.contributor.author | Rull, Ramón |
| dc.contributor.author | Vilalta Solsona, Antonio |
| dc.contributor.author | Lannoy, Emilie |
| dc.contributor.author | Boutros, Celine |
| dc.contributor.author | Benannoune, Naima |
| dc.contributor.author | Tomasic, Gorana |
| dc.contributor.author | Aegerte, Philippe |
| dc.contributor.author | Vidal i Sicart, Sergi |
| dc.contributor.author | Palou, Josep |
| dc.contributor.author | Alós i Hernández, Llúcia |
| dc.contributor.author | Requena, Celia |
| dc.contributor.author | Traves, Víctor |
| dc.contributor.author | Pla, Ángel |
| dc.contributor.author | Bolumar, Isidro |
| dc.contributor.author | Soriano, Virtudes |
| dc.contributor.author | Guillén, Carlos |
| dc.contributor.author | Herrera Ceballos, Enrique |
| dc.date | 2019-03-19T19:06:50Z |
| dc.date | 2019-03-19T19:06:50Z |
| dc.date | 2015-09 |
| dc.date | 2019-03-19T19:06:50Z |
| dc.identifier | 0959-8049 |
| dc.identifier | 660002 |
| dc.identifier | 26072362 |
| dc.identifier.uri | http://hdl.handle.net/2445/130565 |
| dc.description | Introduction: In patients with primary cutaneous melanoma, there is generally a delay between excisional biopsy of the primary tumour and sentinel-node biopsy. The objective of this study is to analyse the prognostic implications of this delay. Patients and method: This was an observational, retrospective, cohort study in four tertiary referral hospitals. A total of 1963 patients were included. The factor of interest was the interval between the date of the excisional biopsy of the primary melanoma and the date of the sentinel-node biopsy (delay time) in the prognosis. The primary outcome was melanoma-specific survival and disease-free survival. Results: A delay time of 40 days or less (hazard ratio (HR), 1.7; confidence interval (CI), 1.2-2.5) increased Breslow thickness (Breslow ⩾2 mm, HR, >3.7; CI, 1.4-10.7), ulceration (HR, 1.6; CI, 1.1-2.3), sentinel-node metastasis (HR, 2.9; CI, 1.9-4.2), and primary melanoma localised in the head or neck were independently associated with worse melanoma-specific survival (all P < 0.03). The stratified analysis showed that the effect of delay time was at the expense of the patients with a negative sentinel-node biopsy and without regression. Conclusion: Early sentinel-node biopsy is associated with worse survival in patients with cutaneous melanoma. |
| dc.format | 24 p. |
| dc.format | application/pdf |
| dc.language | eng |
| dc.publisher | Elsevier B.V. |
| dc.relation | Versió postprint del document publicat a: https://doi.org/10.1016/j.ejca.2015.05.023 |
| dc.relation | European Journal of Cancer, 2015, vol. 51, num. 13, p. 1780-1793 |
| dc.relation | https://doi.org/10.1016/j.ejca.2015.05.023 |
| dc.rights | cc-by-nc-nd (c) Elsevier B.V., 2015 |
| dc.rights | http://creativecommons.org/licenses/by-nc-nd/3.0/es |
| dc.rights | info:eu-repo/semantics/openAccess |
| dc.subject | Melanoma |
| dc.subject | Càncer de pell |
| dc.subject | Nodes limfàtics |
| dc.subject | Melanoma |
| dc.subject | Skin cancer |
| dc.subject | Lymph nodes |
| dc.title | Effect of time to sentinel-node biopsy on the prognosis of cutaneous melanoma |
| dc.type | info:eu-repo/semantics/article |
| dc.type | info:eu-repo/semantics/acceptedVersion |
Related documents
Other documents of the same author
Tejera Vaquerizo, Antonio; Nagore, Eduardo; Puig i Sardà, Susana; Robert, Caroline; Saiag, Philippe; Martín-Cuevas, Paula; Gallego, Elena; Herrera Acosta, Enrique; Aguilera, José; Malvehy, J. (Josep); Carrera Álvarez, Cristina; Cavalcanti, Andrea; Rull, Ramón; Vilalta Solsona, Antonio; Lannoy, Emilie; Boutros, Celine; Benannoune, Naima; Tomasic, Gorana; Aegerte, Philippe; Vidal Sicart, Sergi; Palou, Josep; Alós i Hernández, Llúcia; Requena, Celia; Traves, Víctor; Pla, Ángel; Bolumar, Isidro; Soriano, Virtudes; Guillén, Carlos; Herrera Ceballos, Enrique
Tejera Vaquerizo, Antonio; Nagore, Eduardo; Puig i Sardà, Susana; Robert, Caroline; Saiag, Philippe; Martín-Cuevas, Paula; Gallego, Elena; Herrera Acosta, Enrique; Aguilera, José; Malvehy, J. (Josep); Carrera Álvarez, Cristina; Cavalcanti, Andrea; Rull, Ramón; Vilalta Solsona, Antonio; Lannoy, Emilie; Boutros, Celine; Benannoune, Naima; Tomasic, Gorana; Aegerte, Philippe; Vidal Sicart, Sergi; Palou, Josep; Alós i Hernández, Llúcia; Requena, Celia; Traves, Víctor; Pla, Ángel; Bolumar, Isidro; Soriano, Virtudes; Guillén, Carlos; Herrera Ceballos, Enrique
Márquez Rodas, Iván; Martín González, Manuel; Nagore, Eduardo; Gómez Fernández, Cristina; Avilés Izquierdo, Jose Antonio; Maldonado Seral, Cayetana; Soriano, Virtudes; Majem-Tarruella, Margarita; Palomar, Virginia; Maseda, Rocio; Martín Carnicero, Alfonso; Puertolas, Teresa; Godoy, Elena; Cerezuela, Pablo; Ochoa de Olza, Maria; Campos, Begoña; Perez-Ruiz, Elisabeth; Soria, Ainara; Gil Arnaiz, Irene; Gonzalez Cao, Maria; Galvez, Elisa; Arance, Ana; Belon, Joaquin; de la Cruz-Merino, Luis; Martín Algarra, Salvador; Spanish Multidisciplinary Group of Melanoma (GEM)
Puig, Susana; Potrony, Miriam; Cuellar, Francisco; Puig-Butille, Joan Anton; Carrera, Cristina; Aguilera, Paula; Nagore, Eduardo; Garcia-Casado, Zaida; Requena, Celia; Kumar, Rajiv; Landman, Gilles; Costa Soares de Sá, Bianca; Gargantini Rezze, Gisele; Facure, Luciana; de Avila, Alexandre Leon Ribeiro; Achatz, Maria Isabel; Carraro, Dirce Maria; Duprat Neto, João Pedreira; Grazziotin, Thais C.; Bonamigo, Renan R.; Rey, Maria Carolina W.; Balestrini, Claudia; Morales, Enrique; Molgo, Montserrat; Bakos, Renato Marchiori; Ashton-Prolla, Patricia; Giugliani, Roberto; Larre Borges, Alejandra; Barquet, Virginia; Pérez, Javiera; Martínez, Miguel; Cabo, Horacio; Cohen Sabban, Emilia; Latorre, Clara; Carlos-Ortega, Blanca; Salas-Alanis, Julio C..; Gonzalez, Roger; Olazaran, Zulema; Malvehy, Josep; Badenas, Celia
Maculé Beneyto, Francisco; Segur Vilalta, Josep M.; Vilchez Cavazos, José Félix; Esteban-Navarro, P.; Vidal i Sicart, Sergi; Acosta-Olivo, Carlos