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dc.contributor.author | Balcells, Eva |
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dc.contributor.author | Gimeno Santos, Elena |
dc.contributor.author | Batlle, Jordi de |
dc.contributor.author | Ramon, Maria Antonia |
dc.contributor.author | Rodríguez, Esther |
dc.contributor.author | Benet, Marta |
dc.contributor.author | Farrero, Eva |
dc.contributor.author | Ferrer Monreal, Antonio |
dc.contributor.author | Guerra, Stefano |
dc.contributor.author | Ferrer, Jaume |
dc.contributor.author | Sauleda, Jaume |
dc.contributor.author | Barberà i Mir, Joan Albert |
dc.contributor.author | Agustí García-Navarro, Àlvar |
dc.contributor.author | Rodríguez-Roisin, Robert |
dc.contributor.author | Gea Guiral, Joaquim |
dc.contributor.author | Antó i Boqué, Josep Maria |
dc.contributor.author | García Aymerich, Judith |
dc.contributor.author | PAC-COPD Study Group |
dc.date | 2016-04-11T11:46:40Z |
dc.date | 2016-04-11T11:46:40Z |
dc.date | 2015-01-17 |
dc.date | 2016-04-11T11:46:45Z |
dc.identifier | 1471-2466 |
dc.identifier | 658546 |
dc.identifier | 25595204 |
dc.identifier.uri | http://hdl.handle.net/2445/97242 |
dc.description | Background Under-diagnosis of COPD is an important unmet medical need. We investigated the characteristics and prognosis of hospitalised patients with undiagnosed COPD. Methods The PAC-COPD cohort included 342 COPD patients hospitalised for the first time for an exacerbation of COPD (2004-2006). Patients were extensively characterised using sociodemographic, clinical and functional variables, and the cohort was followed-up through 2008. We defined "undiagnosed COPD" by the absence of any self-reported respiratory disease and regular use of any pharmacological respiratory treatment. Results Undiagnosed COPD was present in 34% of patients. They were younger (mean age 66 vs. 68 years, p = 0.03), reported fewer symptoms (mMRC dyspnoea score, 2.1 vs. 2.6, p < 0.01), and had a better health status (SGRQ total score, 29 vs. 40, p < 0.01), milder airflow limitation (FEV1% ref., 59% vs. 49%, p < 0.01), and fewer comorbidities (two or more, 40% vs. 56%, p < 0.01) when compared with patients with an established COPD diagnosis. Three months after hospital discharge, 16% of the undiagnosed COPD patients had stopped smoking (vs. 5%, p = 0.019). During follow-up, annual hospitalisation rates were lower in undiagnosed COPD patients (0.14 vs. 0.25, p < 0.01); however, this difference disappeared after adjustment for severity. Mortality was similar in both groups. Conclusions Undiagnosed COPD patients have less severe disease and lower risk of re-hospitalisation when compared with hospitalised patients with known COPD. |
dc.format | 9 p. |
dc.format | application/pdf |
dc.language | eng |
dc.publisher | BioMed Central |
dc.relation | Reproducció del document publicat a: http://dx.doi.org/10.1186/1471-2466-15-4 |
dc.relation | BMC Pulmonary Medicine, 2015, vol. 15, p. 4 |
dc.relation | http://dx.doi.org/10.1186/1471-2466-15-4 |
dc.rights | cc-by (c) Balcells, E. et al., 2015 |
dc.rights | http://creativecommons.org/licenses/by/3.0/es |
dc.rights | info:eu-repo/semantics/openAccess |
dc.subject | Malalties pulmonars obstructives cròniques |
dc.subject | Assistència hospitalària |
dc.subject | Estudi de casos |
dc.subject | Epidemiologia |
dc.subject | Chronic obstructive pulmonary diseases |
dc.subject | Hospital care |
dc.subject | Case studies |
dc.subject | Epidemiology |
dc.title | Characterisation and prognosis of undiagnosed chronic obstructive pulmonary disease patients at their first hospitalisation |
dc.type | info:eu-repo/semantics/article |
dc.type | info:eu-repo/semantics/publishedVersion |