Title:
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Identification of intracellular calcium dynamics in stimulated cardiomyocytes
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Author:
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Vallmitjana Lees, Alexander; Barriga, Montserrat; Nenadic, Zoran; Llach, Anna; Álvarez Lacalle, Enrique; Hove-Madsen, Leif; Benítez Iglesias, Raúl
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Other authors:
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Universitat Politècnica de Catalunya. Departament de Física Aplicada; Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial; Universitat Politècnica de Catalunya. NOLIN - Física No-Lineal i Sistemes Fora de l'Equilibri |
Abstract:
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We have developed an automatic method for the
analysis and identification of dynamical regimes in intracellular calcium patterns from confocal calcium images. The method
allows the identification of different dynamical patterns such as spatially concordant and discordant alternans, irregular behavior or phase-locking regimes such as period doubling or halving. The method can be applied to the analysis of different cardiac pathologies related to anomalies at the cellular level such as ventricular reentrant arrhythmias. |
Abstract:
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Peer Reviewed |
Subject(s):
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-Intracellular calcium -Medical image processing -Processament digital -- Biomedicina -Calci en l'organisme |
Rights:
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Document type:
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Article - Published version Conference Object |
Published by:
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IEEE Press. Institute of Electrical and Electronics Engineers
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