Títol:
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Comparing the Health Effects of Ambient Particulate Matter
Estimated Using Ground-Based versus Remote Sensing Exposure
Estimates
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Autor/a:
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Jerrett, Michael; Turner, Michelle C.; Beckerman, Bernardo S.; Pope, C. Arden; Donkelaar, Aaron van; Martin, Randall V.; Serre, Marc; Crouse, Dan; Gapstur, Susan M.; Krewski, Daniel; Diver, W. Ryan; Coogan, Patricia F.; Thurston, George D.; Burnett, Richard T.
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Abstract:
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BACKGROUND: Remote sensing (RS) is increasingly used for
exposure assessment in epidemiological and burden of disease
studies, including those investigating whether chronic exposure
to ambient fine particulate matter (PM2.5) is associated with
mortality. OBJECTIVES: To compare relative risk estimates of
mortality from diseases of the circulatory system for PM2.5
modeled from RS with that for PM2.5 modeled using ground-level
information. METHODS: We geocoded the baseline residence of
668,629 American Cancer Society Cancer Prevention Study II
(CPS-II) cohort participants followed from 1982 to 2004 and
assigned PM2.5 levels to all participants using seven different
exposure models. Most of the exposure models were averaged for
the years 2002-2004, while one RS estimate was for a longer,
contemporaneous period. We used Cox proportional hazards
regression to estimate relative risks (RR) for the association
of PM2.5 with circulatory mortality and ischemic heart disease.
RESULTS: Estimates of mortality risk differed among exposure
models. The smallest relative risk was observed for the RS
estimates that excluded ground-based monitors for circulatory
deaths (RR = 1.02 (95% confidence interval (CI): 1.00-1.04 per
10 microg/m3 increment in PM2.5). The largest relative risk was
observed for the land use regression model that included traffic
information (RR = 1.14, 95% CI: 1.11-1.17 per 10 microg/m3
increment in PM2.5). CONCLUSIONS: We found significant
associations between PM2.5 and mortality in every model;
however, relative risks estimated from exposure models using
ground-based information were generally larger than those
estimated with RS alone. |
Matèries:
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-Malalties coronàries -Mortalitat -Coronary diseases -Mortality |
Drets:
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(c) National Institute of Environmental Health Sciences (NIEHS), 2016
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Tipus de document:
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Article Article - Versió acceptada |
Publicat per:
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National Institute of Environmental Health Sciences (NIEHS)
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