Author:
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Giner Tarrida, Lluís; Mercade, Montse; Torrent Camarero, Sergi; Punset Fuste, Miquel; Pérez Antoñanzas, Román; Delgado, Luis M.; Gil Mur, Francisco Javier
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Abstract:
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Background: The topographical features on the surface of dental implants have been considered as a critical
parameter for enhancing the osseointegration of implants. In this work, we proposed a surface obtained by a
combination of shot blasting and double acid etching. The double acid etching was hypothesized to increase the
submicron topography and hence further stimulate the biological properties of the titanium implant.
Methods: The topographical features (surface roughness and real surface area), wettability and surface chemical
composition were analyzed.
Results: The results showed that the proposed method produced a dual roughness, mainly composed of randomly
distributed peaks and valleys with a superimposed nanoroughness, and hence with an increased specific
surface area. Despite the fact that the proposed method does not introduce significant chemical changes, this
treatment combination slightly increased the amount of titanium available on the surface, reducing potential
surface contaminants. Furthermore, the surface showed increased contact angle values demonstrating an enhanced
hydrophobicity on the surface. The biological behavior of the implants was then assessed by culturing
osteoblast-like cells on the surface, showing enhanced osteoblast adhesion, proliferation and differentiation on
the novel surface.
Conclusions: Based on these results, the described surface with dual roughness obtained by double acid etching
may be a novel route to obtain key features on the surface to enhance the osseointegration of the implant. Our
approach is a simple method to obtain a dual roughness that mimics the bone structure modified by osteoclasts
and increases surface area, which enhances osseointegration of dental implants. |