Unsaturated Oxazolopiperidone Lactams: an Unexpected Domino-type Double Conjugate Addition<br>cyclization Process

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Title:	Unsaturated Oxazolopiperidone Lactams: an Unexpected Domino-type Double Conjugate Addition cyclization Process
Author:	Amat Tusón, Mercedes; Llor Brunés, Núria; Checa Castaño, Begoña; Pérez Bosch, Maria; Bosch Cartes, Joan
Other authors:	Universitat de Barcelona
Abstract:	Reactions of 2-acetylindole enolate with unsaturated oxazolopiperidones 3, 4 and 10 unexpectedly gives pentacyclic dilactams 6, 7 and 11, respectively, resulting from a domino-type process involving two successive conjugate additions and a final cyclization.
Subject(s):	-Compostos heterocíclics -Lactames -Síntesi asimètrica -Heterocyclic compounds -Lactams -Asymmetric synthesis
Rights:	cc-by-nc (c) Amat Tusón, Mercedes et al., 2014 http://creativecommons.org/licenses/by-nc/3.0/es
Document type:	Article Article - Published version
Published by:	Michigan Publishing
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