Título:
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Preparation of benzolactams by Pd(II)-catalyzed carbonylation of N-unprotected arylethylamines
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Autor/a:
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López, Blanca; Rodríguez Ramírez, Aleix; Santos, David; Albert Mach, Joan; Ariza Piquer, Xavier; García Gómez, Jordi; Granell Sanvicente, Jaime Ramón
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Otros autores:
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Universitat de Barcelona |
Abstract:
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An unprecedented NH2-directed Pd(II)-catalytic carbonylation of quaternary aromatic α -amino esters to yield 6-membered 10 benzolactams has been developed. The reaction shows a strong bias to 6-membered lactams over 5-membered ones. The steric hindrance around the amino group seems to be pivotal for the success of the process. |
Materia(s):
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-Pal·ladi (Element químic) -Química organometàl·lica -Reaccions químiques -Lactames -Imines -Palladium -Organometallic chemistry -Chemical reactions -Lactams -Imines |
Derechos:
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(c) López, Blanca et al., 2011
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Tipo de documento:
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Artículo Artículo - Versión aceptada |
Editor:
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Royal Society of Chemistry
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Compartir:
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