dc.contributor.author |
Wang, Shoulei |
dc.contributor.author |
Rodriguez-Escrich, Carles |
dc.contributor.author |
Pericàs, Miquel A. |
dc.date.accessioned |
2018-01-15T16:03:37Z |
dc.date.accessioned |
2018-02-15T10:28:37Z |
dc.date.available |
2018-01-15T16:03:37Z |
dc.date.available |
2018-02-15T10:28:37Z |
dc.date.issued |
2016 |
dc.identifier.uri |
http://hdl.handle.net/2072/226233 |
dc.identifier.uri |
http://hdl.handle.net/2072/305870 |
dc.language.iso |
eng |
dc.publisher |
ACS Publications |
dc.relation |
MINECO |
dc.relation |
DEC Generalitat de Catalunya |
dc.relation |
Severo Ochoa Excellence Accreditation 2014−2018 and Proyectos I+D+I |
dc.relation.ispartof |
Organic Letters |
dc.rights |
© 2016 American Chemical Society |
dc.title |
H-Bond-Directing Organocatalyst for Enantioselective [4+2] Cycloadditions via Dienamine Catalysis |
dc.type |
info:eu-repo/semantics/article |
dc.relation.projectID |
SEV-2013-0319 |
dc.relation.projectID |
CTQ2012-38594-C02-01 |
dc.relation.projectID |
2014SGR827 |
dc.identifier.doi |
https://dx.doi.org/10.1021/acs.orglett.5b03575 |
dc.rights.accessLevel |
info:eu-repo/semantics/openAccess |
dc.description.abstract |
An efficient, highly regio- and stereoselective [4 + 2] cycloaddition reaction to generate tetrahydropyranopyrazole frameworks has been developed. To this end, a dienamine-based catalytic strategy that relies on the H-bond-directing effect of the hydroxy group of a dinaphthylprolinol-type aminocatalyst has been used. This enables the synthesis of multifunctionalized heterocyclic derivatives with three contiguous stereocenters in good yields and excellent enantioselectivities. |