Use of cellular decapping activators by positive-strand RNA viruses

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dc.contributor.author	Jungfleisch, Jennifer, 1986-
dc.contributor.author	Blasco Moreno, Bernat, 1986-
dc.contributor.author	Díez Antón, Juana, 1962-
dc.date	2016
dc.identifier.citation	Jungfleisch J, Blasco-Moreno B, Díez J. Use of cellular decapping activators by positive-strand RNA viruses. Viruses. 2016 Dec 21;8(12). DOI: 10.3390/v8120340
dc.identifier.citation	1999-4915
dc.identifier.citation	http://dx.doi.org/10.3390/v8120340
dc.identifier.uri	http://hdl.handle.net/10230/28042
dc.format	application/pdf
dc.language.iso	eng
dc.publisher	MDPI
dc.rights	https://creativecommons.org/licenses/by/4.0/
dc.rights	info:eu-repo/semantics/openAccess
dc.rights	© 2016 by Jennifer Jungfleisch, Bernat Blasco-Moreno and Juana Díez; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/)
dc.subject	Virus RNA
dc.subject	RNA missatger
dc.title	Use of cellular decapping activators by positive-strand RNA viruses
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion
dc.description.abstract	Positive-strand RNA viruses have evolved multiple strategies to not only circumvent the hostile decay machinery but to trick it into being a priceless collaborator supporting viral RNA translation and replication. In this review, we describe the versatile interaction of positive-strand RNA viruses and the 5'-3' mRNA decay machinery with a focus on the viral subversion of decapping activators. This highly conserved viral trickery is exemplified with the plant Brome mosaic virus, the animal Flock house virus and the human hepatitis C virus.
dc.description.abstract	This work was supported by the Spanish Ministry of Economy and Competitiveness through/ngrant BFU 2013-44629-R and the “Maria de Maeztu” Programme for Units of Excellence in R&D (MDM-2014-0370)

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