Use this identifier to quote or link this document: http://hdl.handle.net/2072/363726

Title:	Stereoselective Catalytic Synthesis of P-Stereogenic Oxides via Hy-drogenative Kinetic Resolution
Author:	Fernández-Pérez, Héctor; Vidal-Ferran, Anton
Abstract:	A highly stereoselective catalytic method for the preparation of structurally diverse P-stereogenic oxides has been developed. The approach relies on the ability of rhodium complexes derived from an enantiopure P–OP ligand to kinetically resolve racemic α,β-unsaturated phosphane oxides by hydrogenation of the C═C motif and formation of highly enantioenriched (or even enantiopure) P-stereogenic oxides. The practicality of the methodology has been demonstrated by the preparation of potentially functional P-chiral molecules for catalytic enantioselective synthesis.
Publication date:	2019-08-28
Subject(s):	54
Rights:	L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/
Pages:	7019 p.
Document type:	Article Article - Accepted version
DOI:	10.1021/acs.orglett.9b02606
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