dc.contributor.author |
Fernández-Pérez, Héctor |
dc.contributor.author |
Vidal-Ferran, Anton |
dc.date.accessioned |
2019-10-31T16:00:42Z |
dc.date.available |
2020-08-27T02:45:05Z |
dc.date.issued |
2019-08-28 |
dc.identifier.uri |
http://hdl.handle.net/2072/363726 |
dc.format.extent |
7019 p. |
dc.language.iso |
eng |
dc.rights |
L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons:http://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.source |
RECERCAT (Dipòsit de la Recerca de Catalunya) |
dc.subject.other |
54 |
dc.title |
Stereoselective Catalytic Synthesis of P-Stereogenic Oxides via Hy-drogenative Kinetic Resolution |
dc.type |
info:eu-repo/semantics/article |
dc.type |
info:eu-repo/semantics/acceptedVersion |
dc.embargo.terms |
12 mesos |
dc.identifier.doi |
10.1021/acs.orglett.9b02606 |
dc.rights.accessLevel |
info:eu-repo/semantics/openAccess |
dc.description.abstract |
A highly stereoselective catalytic method for the preparation of structurally diverse P-stereogenic oxides has been developed. The approach relies on the ability of rhodium complexes derived from an enantiopure P–OP ligand to kinetically resolve racemic α,β-unsaturated phosphane oxides by hydrogenation of the C═C motif and formation of highly enantioenriched (or even enantiopure) P-stereogenic oxides. The practicality of the methodology has been demonstrated by the preparation of potentially functional P-chiral molecules for catalytic enantioselective synthesis. |