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Título:
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The bronchodilator test in chronic obstructive pulmonary disease: interpretation methods
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Autor/a:
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Rodríguez-Carballeira, M.; Heredia, J. L.; Rué i Monné, Montserrat; Quintana, Salvador; Almagro, Pere
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Notas:
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The objective of the study was to evaluate the best method for
interpreting the bronchodilator test (BDT). Five formulas for expressing the BDT
results were analyzed and compared: changes experienced by maximum expiratory
volume in 1 s (FEV1) and forced vital capacity (FVC) measured in milliliters, in
percentage with respect to the baseline, in percentage with respect to the
predicted, in percentage with respect to the possible, and in standardized residuals.
Ninety-eight chronic obstructive pulmonary disease (COPD) patients were submitted
to a respiratory function test on two different days. On each occasion three
spirometries were conducted: basal, post-placebo and post bronchodilator. As a gold
standard, a normality interval was defined using the variability experienced with the
placebo between the two days of the study. The best formulas according to their
sensitivity, specivity and area under receiver operating characteristic (ROC) curve
were the ‘‘standardized residuals’’, with a cut point of .3, and the ‘‘percentage with
respect to the predicted’’ with a cut point of 6%. |
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Materia(s):
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-Chronic obstructive
-Pulmonary disease
-Interpretation of bronchodilator test |
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Derechos:
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(c) Elsevier, 2007
info:eu-repo/semantics/restrictedAccess |
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Tipo de documento:
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article
publishedVersion |
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Editor:
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Elsevier
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Compartir:
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