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Title:
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Baseline residual kidney function and its ensuing rate of decline interact to predict mortality of peritoneal dialysis patients
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Author:
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Pérez Fontán, Miguel; Remón Rodríguez, César; Cunha Naveira, Marta da; Borràs, Mercè; Rodríguez Suárez, Carmen; Quirós Ganga, Pedro; Sánchez Alvarez, Emilio; Rodríguez Carmona, Ana
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Notes:
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Background
Baseline residual kidney function (RKF) and its rate of decline during follow-up are purported
to be reliable outcome predictors of patients undergoing Peritoneal Dialysis (PD).
The independent contribution of each of these factors has not been elucidated.
Method
We report a multicenter, longitudinal study of 493 patients incident on PD and satisfying two
conditions: a glomerular filtration rate (GFR) 1 mL/minute and a daily diuresis 300 mL.
The main variables were the GFR (mean of urea and creatinine clearances) at PD inception
and the GFR rate of decline during follow-up. The main outcome variable was patient mortality.
The secondary outcome variables were: PD technique failure and risk of peritoneal
infection. The statistical analysis was based on a multivariate approach, placing an emphasis
on the interactions between the two main study variables. |
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Rights:
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cc-by (c) Pérez Fontán et al., 2016
http://creativecommons.org/licenses/by/4.0/
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Document type:
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article
publishedVersion |
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Published by:
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Public Library of Science
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