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Title:	What attributes should be included in a discrete choice experiment related to health technologies? A systematic literature review
Author:	Trapero Bertran, Marta; Rodríguez-Martín, Beatriz; López-Bastida, Julio
Notes:	Discrete choice experiments (DCEs) are a way to assess priority-setting in health care provision. This approach allows for the evaluation of individuals’ preferences as a means of adding criteria to traditional quality-adjusted life year analysis. The aim of this systematic literature review was to identify attributes for designing a DCE in order to then develop and validate a framework that supports decision-making on health technologies. Our systematic literature review replicated the methods and search terms used by de Bekker-Grob et al. 2012 and Clark et al. 2014. The Medline database was searched for articles dated between 2008 and 2015. The search was limited to studies in English that reflected general preferences and were choice-based, published as full-text articles and related to health technologies. This study included 72 papers, 52% of which focused on DCEs on drug treatments. The average number of attributes used in all included DCE studies was 5.74 (SD 1.98). The most frequently used attributes in these DCEs were improvements in health (78%), side effects (57%) and cost of treatment (53%). Other, less frequently used attributes included waiting time for treatment or duration of treatment (25%), severity of disease (7%) and value for money (4%). The attributes identified might inform future DCE surveys designed to study societal preferences regarding health technologies in order to better inform decisions in health technology assessment.
Subject(s):	-Disseny d'experiments -Bases de dades -- Cerca -Assistència mèdica -Economia de la salut -Ressenyes sistemàtiques (Investigació mèdica) -Farmàcia -- Presa de decisions -Qüestionaris -Diseño de experimentos -Bases de datos -- Búsqueda de información -Asistencia médica -Economía de la salud -Farmacia -- Toma de decisiones -Experimental design -Health care policy -Database searching -Health economics -Systematic reviews (Medical research) -Drug Therapy -Decision making -Questionnaires
Rights:	© 2019 Trapero-Bertran et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. https://creativecommons.org/licenses/by/4.0/
Document type:	Article Article - Accepted version
Published by:	Public Library of Science
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