Título:
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Genome-wide analysis of the emigrant family of MITEs: amplification dynamics and evolution of genes in Arabidopsis thaliana
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Autor/a:
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Santiago, Néstor; Herráiz, Cristina; Messeguer Peypoch, Xavier; Goñi, Ramon; Casacuberta, Josep Maria
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Otros autores:
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Universitat Politècnica de Catalunya. Departament de Ciències de la Computació |
Abstract:
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MITEs are structurally similar to defective class II elements but
their high copy number and the size and sequence conservation of most
MITE families suggest that they can be amplified by a replicative
mechanism. Here we present a genome-wide analysis of the Emigrant
family of MITEs from Arabidopsis thaliana. In order to be able to
detect divergent ancient copies and low copy number subfamilies with a
different internal sequence we have developed a computer program
(http://www.lsi.upc.es/~alggen) that allows looking for Emigrant
elements based solely on its TIR sequence. Our results show that
different bursts of amplification of one or very few active, or
master, elements have occurred at different times during Arabidopsis
evolution, with an insertion dynamics similar to that of some
SINEs. The analysis of the insertion sites of the Emigrant elements
show that, although Emigrant elements tend to integrate far from ORFs,
the elements inserted within or close to genes are preferentially
maintained during evolution. |
Materia(s):
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-Àrees temàtiques de la UPC::Informàtica -MITE -Arabidopsis thaliana -Genome-wide analysis -Amplification dynamics -Genes evolution -Arabidopsis -Evolution -Emigrant -Master element. |
Derechos:
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Tipo de documento:
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Artículo - Versión publicada Informe |
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