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Title:
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Characteristics of hospitalized cases of Pertussis in Catalonia and Navarra, two regions in the north of Spain
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Author:
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Crespo, Inma; Toledo, Diana; Soldevila, Núria; Jordán, Iolanda; Solano, Rubén; Castilla, Jesús; Caylà, Joan A.; Godoy i García, Pere; Muñoz Almagro, Carmen; Domínguez García, Àngela
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Other authors:
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Working Group on the Transmission of Pertussis in Households |
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Notes:
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Pertussis causes a large number of cases and hospitalizations in Catalonia and Navarra.
We made a study of household cases of pertussis during 2012 and 2013 in order to identify
risk factors for hospitalization in pertussis cases. Each primary case reported triggered the
study of their contacts. Close contacts at home and people who were in contact for >2 hours
during the transmission period of cases were included. The adjusted OR and 95% confidence
intervals (CI) was calculated using logistic regression. A total of 1124 pertussis cases were
detected, of which 14.9% were hospitalized. Inspiratory whoop (aOR: 1.64; CI: 1.02–2.65),
apnoea (aOR: 2.47; CI: 1.51–4.03) and cyanosis (aOR: 15.51; CI: 1.87–128.09) were more
common in hospitalized than in outpatient cases. Hospitalization occurred in 8.7% of correctly-vaccinated
cases, 41.1% of non-vaccinated cases and 9.4% of partially-vaccinated
cases. In conclusion, inspiratory whoop, apnoea and cyanosis were associated factors to
hospitalization while vaccination reduced hospitalizations due to pertussis.
Ministry of Science and Innovation, Institute of Health Carlos III (Project PI11/02557) and Fondo Europeo de Desarrollo Regional (FEDER-Una manera de hacer Europa); the Catalan Agency for the Management of Grants for University Research (AGAUR Grant number 2014/ SGR 1403). |
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Rights:
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cc-by (c) Crespo, Imma et al., 2015
http://creativecommons.org/licenses/by/3.0/es/
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Document type:
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article
publishedVersion |
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Published by:
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Public Library of Science
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Share:
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