dc.contributor.author
Herrera, María Inés
dc.contributor.author
Kölliker Frers, Rodolfo
dc.contributor.author
Barreto, George
dc.contributor.author
Blanco Calvo, Eduardo
dc.contributor.author
Capani, Francisco
dc.date.accessioned
2024-12-05T21:43:37Z
dc.date.available
2024-12-05T21:43:37Z
dc.date.issued
2016-06-02T08:52:41Z
dc.date.issued
2016-06-02T08:52:41Z
dc.identifier
https://doi.org/10.3389/fnagi.2016.00081
dc.identifier
http://hdl.handle.net/10459.1/57150
dc.identifier.uri
http://hdl.handle.net/10459.1/57150
dc.description.abstract
Neuroinflammation involves the activation of glial cells and represents a key element in normal aging and pathophysiology of brain damage. N-acylethanolamides (NAEs), naturally occurring amides, are known for their pro-homeostatic effects. An increase in NAEs has been reported in vivo and in vitro in the aging brain and in brain injury. Treatment with NAEs may promote neuroprotection and exert anti-inflammatory actions via PPARα activation and/or by counteracting gliosis. This review aims to provide an overview of endogenous and exogenous properties of NAEs in neuroinflammation and to discuss their interaction with glial cells.
dc.publisher
Frontiers Media
dc.relation
Reproducció del document publicat a https://doi.org/10.3389/fnagi.2016.00081
dc.relation
Frontiers in Aging Neuroscience, 2016, vol. 8, núm. 81, p. 1-10
dc.rights
cc-by (c) Herrera et al., 2016
dc.rights
info:eu-repo/semantics/openAccess
dc.rights
http://creativecommons.org/licenses/by/3.0/es/
dc.subject
Neuroinflammation
dc.subject
N-acylethanolamides
dc.title
Glial Modulation by N-acylethanolamides in Brain Injury and Neurodegeneration
