Stressful life events during adolescence and risk for externalizing and internalizing psychopathology: a meta-analysis

Abstract

The main objective of the present research was to analyze the relations between stressful life events and the externalizing and internalizing spectra of psychopathology using meta-analytical procedures. After removing the duplicates, a total of 373 papers were found in a literature search using several bibliographic databases, such as the PsycINFO, Medline, Scopus, and Web of Science. Twenty-seven studies were selected for the meta-analytical analysis after applying different inclusion and exclusion criteria in different phases. The statistical procedure was performed using a random/mixed-effects model based on the correlations found in the studies. Significant positive correlations were found in cross-sectional and longitudinal studies. A transactional effect was then found in the present study. Stressful life events could be a cause, but also a consequence, of psychopathological spectra. The level of controllability of the life events did not affect the results. Special attention should be given to the usage of stressful life events in gene-environment interaction and correlation studies, and also for clinical purposes.

Thanks to the Comissionat per a Universitats i Recerca del DIUE, Generalitat de Catalunya (2014SGR1636); the Centre for Biomedical Research in the Mental Health Network (CIBERSAM) Intramural Project (SAM15PI12); the Spanish Ministry of Economy and Competitivity (ES-EUEpiBrain project, grant SAF2015-71526-REDT); the Spanish Ministry of Economy and Competitivity, Instituto de Salud Carlos III (PI15/00097) – Ayuda cofinanciada por el Fondo Europeo de Desarrollo Regional (FEDER). “Una manera de hacer Europa”